Box has been opened, but the individual cartridges are new and factory sealed. Message us with any questions or concerns! Message us if you need it by a certain date and we can work with you to try and make that happen. We stand by all of our items. If anything is not as described or not working, you can return it for a full refund! Please read everything in the description view all pictures carefully so you are set with the proper expectation before purchasing. We Ship World Wide! International buyers please message us for a quote if you do not wish to use the global shipping program, no returns for international sales. Thank you for shopping with us, your business is greatly appreciated!