Changes? MTF Hormone Therapy Spray will dramatically increase your estrogen levels, helping you along your transitioning journey. You will develop womanly features, while blocking any signs of masculinity. The spray works quickly to boost and increase your femininity. You will notice your voice becoming higher and softer, you will grow larger breasts, and a curvier waist to hip ratio, with a pert and feminine bottom. Your penis will reduce in size, skin will become softer body and face hair will be reduced.