Pill Crusher/Grinder - Crushes Multiple Tablets/Pills into a Fine Powder Simple to Use, Quick to Crush, Easy to Clean Twist the adjustment knob to produce coarser or finer powder Instructions: Wash the pill crusher before use. If your pills are very large, it may be easier to break the pill into small pieces first. Take off the lid and place the pills into the body of the pill crusher. Replace the lid and mount the handle on the drive shaft. To alter the coarseness of the crushed pills, remove the container and turn the adjustment knob. Turn the handle clockwise to begin crushing the pills.